High blood pressure (hypertension), very common in patients with chronic kidney disease stage 5 and Alport syndrome, is known to raise these patients risk of death due to cardiovascular complications. Now researchers report that hypertension associated with Alport syndrome might be treated with kidney nerve denervation, a technique that destroys certain blood vessels…
Women with X-linked Alport syndrome (XLAS) can display early onset of end-stage kidney disease, which is often underestimated by doctors. It is important to recognize the clinical signs of the disease to prevent development of kidney failure. In a case report titled “Phenotypic heterogeneity in females with X-linked Alport…
A multidrug cocktail known to halt the progression of kidney disease in non-diabetic patients was seen to effectively improve kidney function and slow disease progression in a small group of patients with Alport syndrome. The study, “A Multidrug, Antiproteinuric Approach to Alport Syndrome: A Ten-Year Cohort Study,” published…
People with the autosomal dominant variant of Alport syndrome can also experience severe symptoms, and may be more prevalent than previously thought, researchers reported. The study, “Study of the True Clinical Progression of Autosomal Dominant Alport Syndrome in a European Population,” was published in the online journal Kidney and Blood Pressure…
More than 100 clinicians, researchers, patient organization and pharmaceutical industry representatives from around the world came together in Göttingen, Germany last year for an International Workshop on Alport Syndrome.
Alport syndrome is a rare genetic condition leading to kidney disease, as well hearing loss and eye problems. The disorder, also going under the name Hereditary Nephritis, Hereditary Deafness and Nephropathy, among others, is more common in boys. According to the National Organization for Rare Disorders (NORD), about…
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